The offline DFC systems include a fraction collector or an auto sampler which will collect the sampled dissolution media. The semi-automated DFC-820SP system is composed of a PTWS 820D staggered stirrer start dissolution bath with built-in individual vessel centering, full tubing installation in PTFE including either in-situ sampling probes or the EPE-820 auto sampling system, a PT-SP8 syringe pump, and a PTFC-2/8SP fraction collector. In this configuration the sampling probes are either always immersed into the media (in-situ) or removed after sampling (EPE-820 system). Both procedures are widely used.

Advantages:
>> The system automates the taking of samples, the most labor intensive stage of a dissolution test
>> Automated sampling eliminates human errors, as equal sampling times and standardized solvent transport offer high reproducibility
>> Excellent reproducibility of sampling volumes and times
>> Offers unattended operation after start of dissolution run
>> Pharma Test offers full system responsibility